Molecular Formular: C11H15N2O8P
Formular Weight: 334.22
Grade: Pharmaceutical Grade
Appearance: White Powder
β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
Nicotinamide mononucleotide (NMN) or Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate is a type of bioactive nucleotide which is naturally formed by the reaction between a phosphate group and a nucleoside containing ribose and nicotinamide.
● In human cells, NMN is available as a source of cellular energy. It was known for its activity as an intermediate in nicotinamide adenine dinucleotide (NAD+) biosynthesis.
● NMN is also used as a substrate for prokaryotic enzymes like NadM in Methanobacterium thermoautotrophicum, NadR in Haemophilus influenza, NadM/Nudix in Francisella tularensis.
● Administration of NMN can compensate for the deficiency of NAD+ caused by these NAD+ consuming enzymes.
● NMN has been found to improve insulin activity and production, resulting in additional metabolic benefits as well as glucose tolerance. In particular, NMN supplements can help work to alleviate metabolic conditions like diabetes, fatty liver disease, and obesity.
● NMN is thought to be critical for healthy aging.
● It promotes Vascular Health and Blood Flow.
● Improves Muscle Endurance and Strength.
● Protects Against Heart Disease.
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